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1

Using polymeric materials to generate an amplified response to molecular recognition events

Sikes, Hadley D., Hansen, Ryan R., Johnson, Leah M., Jenison, Robert, Birks, John W., Rowlen, Kathy L., Bowman, Christopher N.

Journal:

Nature Materials

Year:

2007

Language:

english

File:

PDF, 324 KB

english, 2007

2

A reaction-diffusion model of cytosolic hydrogen peroxide

Lim, Joseph B., Langford, Troy F., Huang, Beijing K., Deen, William M., Sikes, Hadley D.

Journal:

Free Radical Biology and Medicine

Year:

2016

Language:

english

File:

PDF, 647 KB

english, 2016

3

Portable, Constriction–Expansion Blood Plasma Separation and Polymerization-Based Malaria Detection

Shatova, Tatyana A., Lathwal, Shefali, Engle, Marissa R., Sikes, Hadley D., Jensen, Klavs F.

Journal:

Analytical Chemistry

Year:

2016

Language:

english

File:

PDF, 520 KB

english, 2016

4

Can Fish and Cell Phones Teach Us about Our Health?

Lee, Michael A., Duarte, Carlos M., Eguíluz, Víctor M., Heller, Daniel A., Langer, Robert, Meekan, Mark G., Sikes, Hadley D., Srivastava, Mani, Strano, Michael S., Wilson, Rory P.

Journal:

Year:

2019

Language:

english

File:

PDF, 3.43 MB

english, 2019

5

Polymerization-based amplification for target-specific colorimetric detection of amplified Mycobacterium tuberculosis DNA on cellulose

Yee, Emma H., Sikes, Hadley D.

Journal:

Year:

2020

Language:

english

File:

PDF, 502 KB

english, 2020

6

Kinetic modeling of H2O2 dynamics in the mitochondria of HeLa cells

Stein, Kassi T., Moon, Sun Jin, Nguyen, Athena N., Sikes, Hadley D., Held, Jason M.

Journal:

PLoS Computational Biology

Year:

2020

File:

PDF, 2.81 MB

2020

7

Functional heterologous expression and purification of a mammalian methyl-CpG binding domain in suitable yield for DNA methylation profiling assays

Mary E. Boyd, Brandon W. Heimer, Hadley D. Sikes

Journal:

Protein Expression and Purification

Year:

2012

Language:

english

File:

PDF, 784 KB

english, 2012

8

Synthesis of Ferrocenethiols Containing Oligo(phenylenevinylene) Bridges and Their Characterization on Gold Electrodes

Dudek, Stephen P., Sikes, Hadley D., Chidsey, Christopher E. D.

Journal:

Journal of the American Chemical Society

Year:

2001

Language:

english

File:

PDF, 86 KB

english, 2001

9

Systematic Study of Fluorescein-Functionalized Macrophotoinitiators for Colorimetric Bioassays

Lee, Jungkyu K., Heimer, Brandon. W., Sikes, Hadley D.

Journal:

Biomacromolecules

Year:

2012

Language:

english

File:

PDF, 3.74 MB

english, 2012

10

Impact of Dissociation Constant on the Detection Sensitivity of Polymerization-Based Signal Amplification Reactions

Kaastrup, Kaja, Chan, Leslie, Sikes, Hadley D.

Journal:

Analytical Chemistry

Year:

2013

Language:

english

File:

PDF, 1.64 MB

english, 2013

11

Quantifying intracellular hydrogen peroxide perturbations in terms of concentration

Huang, Beijing K., Sikes, Hadley D.

Journal:

Year:

2014

Language:

english

File:

PDF, 1.17 MB

english, 2014

12

Photoelectron Spectroscopy to Probe the Mechanism of Electron Transfer through Oligo(phenylene vinylene) Bridges

Sikes, Hadley D., Sun, Yun, Dudek, Stephen P., Chidsey, Christopher E. D., Pianetta, Piero

Journal:

Journal of Physical Chemistry B

Year:

2003

Language:

english

File:

PDF, 64 KB

english, 2003

13

Interfacial Electron-Transfer Kinetics of Ferrocene through Oligophenyleneethynylene Bridges Attached to Gold Electrodes as Constituents of Self-Assembled Monolayers: Observation of a Nonmonotonic Distance Dependence

Smalley, John F., Sachs, Sandra B., Chidsey, Christopher E. D., Dudek, Stephen P., Sikes, Hadley D., Creager, Stephen E., Yu, C. J., Feldberg, Stephen W., Newton, Marshall D.

Journal:

Journal of the American Chemical Society

Year:

2004

Language:

english

File:

PDF, 295 KB

english, 2004

14

In-depth characterization of the fluorescent signal of HyPer, a probe for hydrogen peroxide, in bacteria exposed to external oxidative stress

Lim, Joseph B., Barker, Kimberly A., Huang, Beijing K., Sikes, Hadley D.

Journal:

Journal of Microbiological Methods

Year:

2014

Language:

english

File:

PDF, 1.23 MB

english, 2014

15

Visual Detection of Labeled Oligonucleotides Using Visible-Light-Polymerization-Based Amplification

Hansen, Ryan R., Sikes, Hadley D., Bowman, Christopher N.

Journal:

Biomacromolecules

Year:

2008

Language:

english

File:

PDF, 935 KB

english, 2008

16

Polymerization-based signal amplification under ambient conditions with thirty-five second reaction times

Kaastrup, Kaja, Sikes, Hadley D.

Journal:

Year:

2012

Language:

english

File:

PDF, 397 KB

english, 2012

17

Polymerization-based signal amplification for paper-based immunoassays

Badu-Tawiah, Abraham K., Lathwal, Shefali, Kaastrup, Kaja, Al-Sayah, Mohammad, Christodouleas, Dionysios C., Smith, Barbara S., Whitesides, George M., Sikes, Hadley D.

Journal:

Year:

2015

Language:

english

File:

PDF, 709 KB

english, 2015

18

Balancing the Initiation and Molecular Recognition Capabilities of Eosin Macroinitiators of Polymerization-Based Signal Amplification Reactions

Lee, Jungkyu K., Sikes, Hadley D.

Journal:

Macromolecular Rapid Communications

Year:

2014

Language:

english

File:

PDF, 2.87 MB

english, 2014

19

Editorial overview: Analytical biotechnology

Sikes, Hadley D, Zamboni, Nicola

Journal:

Current Opinion in Biotechnology

Year:

2015

Language:

english

File:

PDF, 412 KB

english, 2015

20

Analysis of the lifetime and spatial localization of Hydrogen peroxide generated in the cytosol using a reduced kinetic model

Lim, Joseph B., Huang, Beijing K., Deen, William M., Sikes, Hadley D.

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 1.44 MB

english, 2015

21

A quantitative analysis of peroxy-mediated cyclic regeneration of eosin under oxygen-rich photopolymerization conditions

Wong, Jisam, Kaastrup, Kaja, Aguirre-Soto, Alan, Sikes, Hadley D.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.65 MB

english, 2015

22

Staged inertial microfluidic focusing for complex fluid enrichment

Reece, Amy E., Kaastrup, Kaja, Sikes, Hadley D., Oakey, John

Journal:

Year:

2015

Language:

english

File:

PDF, 1.07 MB

english, 2015

23

Interpreting Heterogeneity in Response of Cells Expressing a Fluorescent Hydrogen Peroxide Biosensor

Huang, Beijing K., Ali, Sohail, Stein, Kassi T., Sikes, Hadley D.

Journal:

Biophysical Journal

Year:

2015

Language:

english

File:

PDF, 1.62 MB

english, 2015

24

UV-Vis/FT-NIR in situ monitoring of visible-light induced polymerization of PEGDA hydrogels initiated by eosin/triethanolamine/O 2

Kaastrup, Kaja, Aguirre-Soto, Alan, Wang, Chen, Bowman, Christopher N., Stansbury, Jeffrey W., Sikes, Hadley D.

Journal:

Polymer Chemistry

Year:

2016

Language:

english

File:

PDF, 1.80 MB

english, 2016

25

A method for designing instrument-free, quantitative immunoassays

Lathwal, Shefali, Sikes, Hadley D.

Journal:

Analytical Chemistry

Year:

2016

Language:

english

File:

PDF, 956 KB

english, 2016

26

Using sensors and generators of H2O2 to elucidate the toxicity mechanism of piperlongumine and phenethyl isothiocyanate

Huang, Beijing Kara, Langford, Troy F., Sikes, Hadley D.

Journal:

Antioxidants & Redox Signaling

Year:

2016

Language:

english

File:

PDF, 1.21 MB

english, 2016

27

Assessment of colorimetric amplification methods in a paper-based immunoassay for diagnosis of malaria

Lathwal, Shefali, Sikes, Hadley D.

Journal:

Year:

2016

Language:

english

File:

PDF, 865 KB

english, 2016

28

FRET-Based Probe for H2O2-Induced Peroxiredoxin-2 Oxidation

Langford, Troy, Sikes, Hadley

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 171 KB

english, 2015

29

Interpreting Heterogeneity in the Response of Cells Expressing a Fluorescent Biosensor to Stimulation with Hydrogen Peroxide

Sikes, Hadley D.

Journal:

Free Radical Biology and Medicine

Year:

2015

Language:

english

File:

PDF, 186 KB

english, 2015

30

Insights into electron leakage in the reaction cycle of cytochrome P450 BM3 revealed by kinetic modeling and mutagenesis

Lim, Joseph B., Barker, Kimberly A., Eller, Kristen A., Jiang, Linda, Molina, Veronica, Saifee, Jessica F., Sikes, Hadley D.

Journal:

Protein Science

Year:

2015

Language:

english

File:

PDF, 1005 KB

english, 2015

31

Using nanobiotechnology to increase the prevalence of epigenotyping assays in precision medicine

Heimer, Brandon W., Tam, Brooke E., Minkovsky, Alissa, Sikes, Hadley D.

Journal:

Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology

Year:

2016

Language:

english

File:

PDF, 862 KB

english, 2016

32

The Impact of Continuous Oxygen Flux in a Thin Film Photopolymerization Reaction with Peroxy-Mediated Regeneration of Initiator

Wong, Jisam, Sikes, Hadley D.

Journal:

Macromolecular Theory and Simulations

Year:

2016

Language:

english

File:

PDF, 2.71 MB

english, 2016

33

Modulating and Measuring Intracellular H 2 O 2 Using Genetically Encoded Tools to Study Its Toxicity to Human Cells

Huang, Beijing K., Stein, Kassi T., Sikes, Hadley D.

Journal:

ACS Synthetic Biology

Year:

2016

Language:

english

File:

PDF, 962 KB

english, 2016

34

Redox regulation: Scaffolding H2O2 signaling

Sikes, Hadley D

Journal:

Nature Chemical Biology

Year:

2017

Language:

english

File:

PDF, 171 KB

english, 2017

35

Addressing Barriers to the Development and Adoption of Rapid Diagnostic Tests in Global Health

Miller, Eric, Sikes, Hadley D.

Journal:

Nanobiomedicine

Year:

2015

Language:

english

File:

PDF, 1013 KB

english, 2015

36

Detection of Biomarkers of Periodontal Disease in Human Saliva Using Stabilized, Vertical Flow Immunoassays

Yee, Emma H., Lathwal, Shefali, Shah, Pratik P., Sikes, Hadley D.

Journal:

Year:

2017

Language:

english

File:

PDF, 428 KB

english, 2017

37

Paper-based diagnostics in the antigen-depletion regime: high-density immobilization of rcSso7d-cellulose-binding domain fusion proteins for efficient target capture

Miller, Eric A., Baniya, Subha, Osorio, Daniel, Al Maalouf, Yara Jabbour, Sikes, Hadley D.

Journal:

Biosensors and Bioelectronics

Year:

2017

Language:

english

File:

PDF, 1.67 MB

english, 2017

38

A mathematical analysis of Prx2-STAT3 disulfide exchange rate constants for a bimolecular reaction mechanism

Langford, Troy F., Deen, William M., Sikes, Hadley D.

Journal:

Free Radical Biology and Medicine

Year:

2018

Language:

english

File:

PDF, 791 KB

english, 2018

39

An Examination of Critical Parameters in Hybridization-Based Epigenotyping using Magnetic Microparticles

Tam, Brooke E., Hao, Yining, Sikes, Hadley D.

Journal:

Biotechnology Progress

Year:

2018

Language:

english

File:

PDF, 1.22 MB

english, 2018

40

Excitation of metastable intermediates in organic photoredox catalysis: Z-scheme approach decreases catalyst inactivation

Aguirre-Soto, Alan, Kaastrup, Kaja, Kim, Seunghyeon, Ugo-Beke, Kasite, Sikes, Hadley D.

Journal:

Year:

2018

Language:

english

File:

PDF, 977 KB

english, 2018

41

Quantitative analysis of cytosolic and mitochondrial H2O2 metabolism and toxicity in human epithelial cells

Sikes, Hadley D.

Journal:

Free Radical Biology and Medicine

Year:

2018

Language:

english

File:

PDF, 39 KB

english, 2018

42

Design principles for enhancing sensitivity in paper-based diagnostics via large-volume processing

Miller, Eric A, Jabbour Al Maalouf, Yara, Sikes, Hadley D.

Journal:

Analytical Chemistry

Year:

2018

Language:

english

File:

PDF, 638 KB

english, 2018

43

A unique model for SDH-deficient GIST: an endocrine-related cancer

Powers, James F, Cochran, Brent, Baleja, James D, Sikes, Hadley D, Zhang, Xue, Lomakin, Inna, Langford, Troy F, Stein, Kassi Taylor, Tischler, Arthur S

Journal:

Endocrine Related Cancer

Year:

2018

Language:

english

File:

PDF, 10.62 MB

english, 2018

44

Phenolphthalein-Conjugated Hydrogel Formation under Visible Light Irradiation for Reducing Variability of Colorimetric Biodetection

Kim, Seunghyeon, Sikes, Hadley D.

Journal:

ACS Applied Bio Materials

Year:

2018

Language:

english

File:

PDF, 755 KB

english, 2018

45

Mitochondrial H 2 O 2 generation using a tunable chemogenetic tool to perturb redox homeostasis in human cells and induce cell death

Stein, Kassi T., Moon, Sun Jin, Sikes, Hadley D.

Journal:

ACS Synthetic Biology

Year:

2018

File:

PDF, 1.34 MB

2018

46

Improved Ordering in Low Molecular Weight Protein–Polymer Conjugates Through Oligomerization of the Protein Block

Paloni, Justin M., Miller, Eric A., Sikes, Hadley D., Olsen, Bradley D.

Journal:

Biomacromolecules

Year:

2018

File:

PDF, 3.46 MB

2018

47

Monitoring the action of redox-directed cancer therapeutics using a human peroxiredoxin-2-based probe

Langford, Troy F., Huang, Beijing K., Lim, Joseph B., Moon, Sun Jin, Sikes, Hadley D.

Journal:

Nature Communications

Year:

2018

Language:

english

File:

PDF, 1.26 MB

english, 2018

48

Mitochondrial H 2 O 2 generation using a tunable chemogenetic tool to perturb redox homeostasis in human cells and induce cell death

Stein, Kassi T., Moon, Sun Jin, Sikes, Hadley D.

Journal:

ACS Synthetic Biology

Year:

2018

Language:

english

File:

PDF, 1.34 MB

english, 2018

49

Improved Ordering in Low Molecular Weight Protein–Polymer Conjugates Through Oligomerization of the Protein Block

Paloni, Justin M., Miller, Eric A., Sikes, Hadley D., Olsen, Bradley D.

Journal:

Biomacromolecules

Year:

2018

Language:

english

File:

PDF, 3.46 MB

english, 2018

50

On the role of N -vinylpyrrolidone in the aqueous radical-initiated copolymerization with PEGDA mediated by eosin Y in the presence of O 2

Aguirre-Soto, Alan, Kim, Seunghyeon, Kaastrup, Kaja, Sikes, Hadley D.

Journal:

Polymer Chemistry

Year:

2019

Language:

english

File:

PDF, 1.77 MB

english, 2019